Resources by Category: "PGS"

Whole genome prediction for preimplantation genetic diagnosis

Kumar A, Ryan A, Kitzman JO, Wemmer N, Snyder MW, Sigurjonsson S, et al. Whole genome prediction for preimplantation genetic diagnosis. Genome Med. 2015;7(1):35. PubMed PMID: 26019723; PubMed Central PMCID: PMCPMC4445980. DOI: 10.1186/s13073-015-0160-4.

Does the S phase have an impact on the accuracy of comparative genomic hybridization profiles in single fibroblasts and human blastomeres?

Ramos, Laia, Javier Del Rey, Gemma Daina, Olga Martinez-Passarell, Mariona Rius, Dolores Tuñón, Mercedes Campillo, Jordi Benet, and Joaquima Navarro. 2013. “Does the S Phase Have an Impact on the Accuracy of Comparative Genomic Hybridization Profiles in Single Fibroblasts and Human Blastomeres?” Fertility and Sterility(December 4): 11. DOI:10.1016/j.fertnstert.2013.10.031.

Two Methods for High-Throughput NGS Template Preparation for Small Clinical Samples Without Automation

J. Langmore, E. Kamberov, T. Tesmer, M. Mastronardi (Rubicon Genomics, Ann Arbor) Clinical samples are difficult to prepare for NGS, because of the small amounts of formalin-fixed tissue, plasma, urine, and single-cell DNA available from patients. Conventional whole genome amplification methods are too biased for NGS applications, and the existing NGS preparation kits require intermediate… Read more »