Resources by Category: "ThruPLEX"

Genomic Characterization of Metformin Hepatic Response

Marcelo R. Luizon, Walter L. Eckalbar, Yao Wang, Stacy L. Jones, Robin, P. Smith, Megan Laurance5, Lawrence Lin1, Paul J. Gallins6, Amy S. Etheridge, Fred Wright, Yihui Zhou, Cliona Molony, Federico Innocenti, Sook Wah Yee, Kathleen, M. Giacomini, Nadav Ahituv. PLOS Genetics. Published: November 30, 2016. http://dx.doi.org/10.1371/journal.pgen.1006449.

FOXA1, GATA3 and PPARɣ Cooperate to Drive Luminal Subtype in Bladder Cancer: A Molecular Analysis of Established Human Cell Lines

Joshua I. Warrick, Vonn Walter, Hironobu Yamashita, Eunah Chung, Lauren Shuman, Vasty Osei Amponsa, Zongyu Zheng, Wilson Chan, Tiffany L. Whitcomb, Feng Yue, Tejaswi Iyyanki, Yuka I. Kawasawa, Matthew Kaag, Wansong Guo, Jay D. Raman, Joo-Seop Park & David J. DeGraff.  Scientific Reports 6, Article number: 38531 (2016). doi:10.1038/srep38531

Characterization of the cytokinin-responsive transcriptome in rice

  Tracy Raines, Ivory C. Blakley, Yu-Chang Tsai, Jennifer M. Worthen, José Manuel Franco Zorrilla, Roberto Solano, G. Eric Schaller, Ann E. Loraine and Joseph J. Kieber. BMC Plant Biology. 201616:260. DOI: 10.1186/s12870-016-0932-z  

NGS libraries from cell-free DNA containing molecular tags prepared with ThruPLEX® technology improve ability to detect rare alleles

Matthew Carroll1, Dmitry Goryunov1, Konstantinos Charizanis1, Fang Sun1, Maria Dinkelmann1, Edward Jan1, Kamran Shazand1, Emmanuel Kamberov1, Shawn Quinn2, John Langmore1 1Rubicon Genomics, Inc. • Ann Arbor, MI • 2 Curio Genomics, Inc. Dexter, MI Liquid biopsies provide a non-invasive method to acquire the genetic information provided in cell-free DNA. Next Generation Sequencing enables access to… Read more »

High-Efficiency Detection of Low-Frequency Alleles in Cell-Free DNA

K. Shazand, J. Ning, E. Ranghini, A. Popkie, and J.P. Jerome The ability to detect rare alleles is key to the discovery and characterization of mutations in cancer research. These mutations are found at low frequencies, mainly because of tumor heterogeneity and tumor DNA dilution in the germline background. Cell-free DNA (cfDNA) in plasma provides… Read more »

Fragment Length of Circulating Tumor DNA

Underhill HR, Kitzman JO, Hellwig S, Welker NC, Daza R, Baker DN, Gligorich KM, Rostomily RC, Bronner MP, Shendure J. PLoS Genet. 2016 Jul 18;12(7):e1006162. doi: 10.1371/journal.pgen.1006162.